A Household Yeast Sensor for Cholera: adoption, impact and effectiveness in low-resource settings.
A Household Yeast Sensor for Cholera: adoption, impact and effectiveness in low-resource settings.
(May 2016 - April 2020)
Cholera causes 95,000 deaths worldwide every year, predominantly in low-resource and humanitarian emergency settings. To address this challenge, quicker and more effective diagnostics and surveillance mechanisms are needed.
Scientists at Columbia University are developing a new biosensor intended to assist in the detection of cholera in low-resource settings.
QMU's contribution to this project
To inform the work of Columbia colleagues, our IGHD team is focused on appraising the characteristics of currently available cholera products.
Additionally, we are focused on identifying new disease targets which could benefit from similar innovation approaches.
- About this project
- Partners
- Funding
- Project objectives
- Project publications
2.86 million cases of cholera, causing 95,000 deaths, occur every year.
Diagnosing and detecting these cases in the early stages of an epidemic are vital for controlling the outbreak. There are a range of diagnostic tests currently available, however, their performance and accuracy is variable.
Scientists at Columbia University are developing an innovative biosensor, based on yeast, to assist in the detection of cholera in low-resource settings.
At IGHD we are supporting colleagues at Columbia University in two ways:
1. conducting a comprehensive review of the literature on existing diagnostic products to inform product development,2. identifying new disease targets that could benefit from similar innovative diagnostic approaches.
Our work supports colleagues at Columbia University in the development of an innovative product for cholera diagnosis and surveillance.
This project is funded via National Institutes of Health Grant 5R01AI110794.
Our objectives on this project include:
• Identifying products currently used for cholera diagnosis.
• Collating information on the technical specifications of current cholera diagnostic products.
• Reviewing available data regarding the performance of currently available diagnostic products.
• Identifying new disease targets that could benefit from innovative diagnostic approaches similar to a household yeast sensor.
