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Dietetics, Nutrition and Biological Sciences Research

Dr. Iain Gow

PUBLICATIONS

 

Chapters in Books

 

Gow IF (2001) Resting Serum Insulin is Reduced During Magnesium Infusion in Sheep. In: Rayssiguier Y, Mazur, A., Durlach, J. (Eds). Advances in Magnesium Research: Nutrition and Health. London: John Libbey. p. 385-387.

 

Edwards, CRW, Al-Dujaili, EAS, Boscero, M, Gow IF, and Williams,BC (1982) Peptidergic and monoaminergic regulation of secretion. In: Mantero, F, Biglieri, EG, and Edwards, CRW. (Eds). Serono symposium No. 50. London: Academic Press: 11-18

 

 

Refereed Journal Publications

 

Shennan DB, Thomson J, Gow IF (2006) Osmoregulation of taurine efflux from cultured human breast cancer cells: comparison with volume activated Cl- efflux and regulation by extracellular ATP. Cell Physiol Biochem, 18, 113-22.

 

Shennan DB, Thomson J, Davidson J, Gow IF (2006). Properties of volume-activated taurine efflux from human breast cancer cells. Adv Exp Med Biol, 583, 109-16.

 

Allan GJ, Tonner E, Szymanowska M, Shand JH, Kelly SM, Phillips K, Clegg RA, Gow IF, Beattie J, Flint DJ. (2006) Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action. Endocrinology, 147, 338-49.

 

Gow IF , Thomson J, Davidson J, Shennan DB (2005) The effect of a hyposmotic shock and purinergic agonists on K +(Rb +) efflux from cultured human breast cancer cells. Biochim Biophys Acta, 1712, 52-61.

 

Travers MT, Gow IF, Barber MC, Thomson J, Shennan DB (2004) Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cells. Biochim Biophys Acta, 1661, 106-12.

 

Shennan DB, Thomson J, Gow IF, Travers MT, Barber MC (2004) L-leucine transport in human breast cancer cells ( MCF-7 and MDA-MB-231): kinetics, regulation by estrogen and molecular identity of the transporter. Biochim Biophys Acta, 1664, 206-16.

 

Gow IF , Mitchell E, Wait M (2003) Adrenergic receptors in the bovine mammary artery. Biochem Pharmacol, 65, 1747-53.

 

Gow IF , Mitchell E, Wait M (2003). Intravenous magnesium reduces the rate of glucose disposal in lactating sheep. Exp Physiol, 88, 533-40.

 

Gow IF (2002). Changes in Ionised Mg 2+ and Ca 2+ in Maternal Serum During Weaning in Goats. Magnesium Research, 15, 199-202.

 

Shennan DB, Grant AC, Gow IF (2002). The effect of hyposmotic and isosmotic cell swelling on the intracellular [Ca 2+] in lactating rat mammary acinar cells. Molecular & Cellular Biochemistry, 233, 91-7.

 

Gow IF (2001) Measurement of ionised magnesium in HEPES-buffered serum samples. Analytica Chimica Acta, 432, 143-149.

 

Gow IF (2000) Response of isolated ruminant mammary arteries to the long R3 analogue of insulin-like growth factor I.Experimental Physiology, 85, 275-9.

 

Grant AC, Gow IF, Zammit VA, Shennan DB (2000) Regulation of protein synthesis in lactating rat mammary tissue by cell volume. Biochimica et Biophysica Acta, 1475, 39-46.

 

Shennan DB, Gow IF (2000) Volume-activated K(+)(Rb(+)) efflux in lactating rat mammary tissue. Biochimica et Biophysica Acta, 1509, 420-8.

 

Gow IF , Cumming A, Sykes A (1999) Suppression of aggregation and calcium mobilisation in bovine platelets by external magnesium. Platelets, 10, 306-311.

 

Gow IF , Flatman PW, Ellis D (1999) Lithium induced changes in intracellular free magnesium concentration in isolated rat ventricular myocytes. Molecular and Cellular Biochemistry, 198, 129-133.

 

Handy RD, Gow IF, Ellis D, Flatman PW (1996) Na-dependent regulation of intracellular free magnesium concentration in isolated rat ventricular myocytes. Journal of Molecular & Cellular Cardiology, 28, 1641-51.

 

Gow IF , Ellis D (1996) Transmembrane movements of lithium in isolated sheep-heart Purkinje fibres. Journal of Molecular and Cellular Cardiology, 28, 299-310.

 

Do E, Baudet S, Gow IF, Ellis D, Noireaud J (1995) Intracellular pH During Hypoxia in Normal and Hypertrophied Right Ventricle of Ferret Heart. Journal of Molecular and Cellular Cardiology, 27, 927-939.

 

Gow IF , Latham T, Ellis D, Flatman PW (1995) Measurement of intracellular ionized magnesium concentration in myocytes isolated from the septomarginal band of sheep hearts. Magnesium Research, 8, 223-32.

 

Waugh C, Dockrell M, Edwards CRW, Elder A, Flapan A, Mitchell J, Williams BC, Gow IF (1994) Simultaneous measurement by radioimmunoassay of ß- thromboglobulin and serotonin released from thrombin-stimulated human platelets. European Journal of Haematology, 52, 180-181.

 

Gow IF , Dockrell M, Edwards CRW, Elder A, Grieve J, Kane G, Padfield PL, Waugh CJ, Williams BC (1992) The sensitivity of human blood platelets to the aggregating agent ADP during different dietary sodium intakes in healthy men. European Journal of Clinical Pharmacology, 43, 635-638.

 

Gow IF , Dockrell, M, Waugh, C, and Williams, BC (1991) The relationship between platelet and platelet-rich plasma serotonin measurements. Platelets, 2, 161-162

 

Gow IF , Flapan AD, Morris M, Davies E, Williams BC, Padfield PL, Shaw TRD, Edwards CRW (1991) A Lack of Effect of Captopril on Platelet-Aggregation in Patients with Congestive-Heart-Failure. European Journal of Clinical Pharmacology, 41, 47-49.

 

Gow IF , Ellis D (1990) Effect of Lithium on the Intracellular Potassium Concentration in Sheep Heart Purkinje-Fibers. Experimental Physiology, 75, 427-430.

 

Gow IF , Jones DB, Billett J, France AJ, Edwards CR (1988) Platelet serotonin concentration in patients with finger-clubbing [letter]. Lancet, 2, 579.

 

Gow IF , Corrie JET, Edwards CRW, Williams BC. The Stability of Tritiated Serotonin Stored at 4-Degrees-C Implications for Platelet Uptake Studies. Thrombosis Research 1988; 52: 263-268.

 

Gow IF , Corrie JE, Williams BC, Edwards CR (1987) Development and validation of an improved radioimmunoassay for serotonin in platelet-rich plasma. Clinica Chimica Acta, 162, 175-88.

 

Gow IF , Padfield PL, Reid M, Stewart SE, Edwards CR, Williams BC (1987) High sodium intake increases platelet aggregation in normal females. Journal of Hypertension 5, S243-6

 

 

Published Presentations

 

Blatchford, D & Gow, IF (2006) Contraction induced by noradrenaline or serotonin is increased in the rat superficial epigastric artery during lactation. From the University of Oxford, Winter 2006 Meeting: Proceedings of the British Pharmacological Society http://www.pa2online.org/abstracts/Vol4Issue2abst137P.pdf

 Gow IF , Faulkner A (2000) Changes is serum ionised magnesium in lactating sheep during an intravenous glucose-tolerance test. Biochemical Society Transactions, 28, A26.

 

Gow IF , Burns C, Shennan DB (1998) Volume-activated calcium transport in lactating rat mammary tissue. Biochemical Society Transactions, 26, S389.

 

Riches PL, Gow IF (1998) The effect of lithium on bovine blood platelet function. Biochemical Society Transactions, 26, S391.

 

Brown, SJ, Gow, IF, Williams, BC, Hayes, PC, and Dillon, J (1997) Zinc protoporphyrin alters the free calcium level in platelets from cirrhotics. Scottish Medical Journal, 42, p25-26

 

Gow IF , Cumming A (1997) The effect of external magnesium on cytosolic free ionized calcium in bovine blood platelets. Journal of Physiology - London, 499P, P61-62.

Handy RD, Ellis D, Gow IF, Flatman PW (1996) Regulation of intracellular ionized magnesium concentration by Na +-Mg 2+ exchange in isolated rat ventricular myocytes. Journal of Physiology - London, 495P, P168

Gow IF , Sykes AJ (1995) Magnesium Prolongs the Duration of Thrombin-Induced Shape Changes in Bovine Platelets. British Journal of Pharmacology, 116, P407.

Gow IF , Ellis D (1992) Factors affecting the steady-state distribution of lithium in the sheep-heart Purkinje fibre. Biochemical Society Transactions, 20, 15S.

 

Elder, AT, Gow, IF, Dockrell, M, Waugh, C, Williams, BC, Flapan, AD, and Shaw, TRD (1992) Reduced intraplatelet serotonin in unstable angina and acute myocardial infarction. European Heart Journal, 13, (Suppl.), 265

 

Waugh CJ, Gow IF, Edwards CRW, Williams BC (1989). Application of a Novel Radioimmunoassay for Serotonin in the Detection of Aromatic L-Amino-Acid Decarboxylase Activity in Isolated Renal Cortical-Cells. Biochemical Society Transactions, 17, 163-164.

 

Gow IF , Padfield PL, Reid M, Stewart S, Williams BC, Edwards CRW (1986) Sodium-Intake, Platelet-Aggregation, and Serotonin Levels in Normal Females. Journal of Endocrinology, 111, s40.

 

Shaikh, S, Williams, BC, Gow, IF, Macdonald, A, and Edwards,CRW (1986) The effects of altering endogenous serotonin levels in the rat on the steroidogenic response of isolated zona glomerulosa cells to angiotensin II (AII) and serotonin (5HT) in vitro. Journal of Endocrinology, 111, s93

 

 

 

Reviews

 

Gow IF (1999) Cardiovascular Effects of Insulin-like Growth Factor I. Hannah Research Institute Yearbook 38-47

 

Gow IF (1993) Mechanisms of lithium action: I. Ions and ion movement - potassium and the sodium-potassium pump. Reviews in Contemporary Pharmacotherapy, 4, 288-289.

 

Gow IF , Williams BC (1989) Immunoassays for Antigens. Current Opinion in Immunology, 1, 940-947.

 

 

Research Reports and Other Publications

 

Gow IF (2009) Final Report to the Scottish Government Rural and Environment Research and Analysis Directorate (RERAD). Pharmacological & Physiological Characterisation of the Rat Mammary Artery at Different Stages of Reproduction, 1-25

 

Gow IF (2006) Final Report to Scottish Executive Environment and Rural Affairs Department (SEERAD) Science and Research Group, Project HRI/131/03 Potassium and Chloride Transport in Normal and Tumorigenic Mammary Epithelial Cells , 1-5

 

Gow IF (2003) Final Report to Scottish Executive Environment and Rural Affairs Department (SEERAD) Agricultural and Biological Research Group, Project HRI/004/01 Regulation of tone in ruminant and rat mammary arteries 1-8

 

Gow IF (1999) Progress Report to Scottish Executive Environment and Rural Affairs Department (SEERAD) Agricultural and Biological Research Group, Project HRI/003/98 The role of nutritional and nutritionally-derived events in regulating mammary metabolism and milk production 1-5

 

 

Unpublished Conference Proceedings

 

Blatchford, D, Coats, P, Gordon, P and Gow, IF (2010) Mammary Artery Adrenergic Response in the Reproducing Rat Scottish Cardiovascular Forum, Glasgow, February 2010

Gow IF (2000). Resting serum insulin is reduced during magnesium infusion in sheep. In: Mag 2000, Vichy, 2000. p176

 

Binnie JAH, Wilson NH, Williams BC, Gow IF (1993) The effect of magnesium on human blood platelet aggregation and cytosolic calcium levels. British Society for Cardiovascular Research Symposium on Cardiac Ischaemia No. 4.

 

Gow IF , Flatman PW, Ellis D (1993) Effects of isoprenaline on free calcium and magnesium levels in isolated rat ventricular cells. XXXII Congress of the International Union of Physiological Sciences, 207.2/P.

 

Miller, S, Waugh, C, Morris, M, Gow, IF, Rossiter, S, Williams, BC, and Edwards,CRW (1989) Effects of aspirin on the renin-angiotensin-aldosterone system in the rat. 8 th Joint Meeting of British Endocrine Societies, April 1989

 

Waugh CJ, Gow IF, Mitchell J, Pepper D, Williams BC, Edwards CRW (1989). The release of serotonin from thrombin-stimulated human platelets measured by radioimmunoassay - a comparison with ß- thromboglobulin. International Symposium on Serotonin, Florence, March 1989, p150.

 

Gow, IF , Dockrell, M, Elder, A, Flapan AD and Williams, BC (1989) The relationship between platelet serotonin concentration and ADP-induced in vitro aggregation. International Symposium on Serotonin, Florence , March 1989, p139.

 

McLeod, L, Davies, E, Rossiter, S, Nisbet, J, Gow, IF, Edwards, CRW, and Williams, BC (1988) Activation of the renin-angiotensin-aldosterone system in the conscious rat by 5- hydroxytryptophan. 7 th Joint Meeting of British Endocrine Societies, Exeter, 1988; abstract 46

 

Gow, IF , Corrie, JET, Williams, BC, and Edwards, CRW (1986) An improved RIA for serotonin. Clinical Science, 70, s13

 

 

 

Going, JJ, Harmer, AJ, Gow, IF, and Edwards, CRW (1985) Hypersalivation and local pain associated with ectopic substance P production by a metastatic laryngeal carcinoid. 4 th Joint Meeting of British Endocrine Societies, Oxford 1985; abstract72

 

Williams, BC, Green, DK, Al-Dujaili, EAS, Gow, IF and Edwards,CRW (1982) A novel method of separation of endocrine cells using a fluorescence-activated cell sorter (FACS) to measure endogenous fluorescence. American Endocrine Society meeting 1982; abstract 9

 

 

 

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